Infectious Complications of Bio-Alcamid Filler Used for HIV-Related Facial Lipoatrophy
نویسندگان
چکیده
منابع مشابه
Infectious complications of Bio-Alcamid filler used for HIV-related facial lipoatrophy.
BACKGROUND Human immunodeficiency virus (HIV)-related facial lipoatrophy is a devastating adverse effect of antiretroviral therapy. At this time, the most viable treatment option is cosmetic surgery with synthetic fillers. Bio-Alcamid has many advantages over other fillers, and has become widely used. The objective of this study was to determine the incidence rate of infectious complications as...
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Lipoatrophy of the face in HIV seropositives are not susceptible to satisfactory correction by using single cosmetic surgery. The limitation of the available filler products to augment and to correct the facial defects in facial lipoatrophy is mainly inherent in the amount of substance that can be implanted for the correction of lipoatrophy. Using Bio-Alcamid, which is an injectable, biocompati...
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Avariety of injectable fillers have been employed to correct the stigmatizing facial lipoatrophy associated with HIV infection. A novel filler is Bio-Alcamid (Bio-Alcamid, Polymekon, Milan, Italy), which has been described as an injectable ‘‘endoprosthesis.’’ This nonbiodegradable filler is composed of 96% water and 4% synthetic polymer polyalkylamide and is purported to be biologically inert. ...
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Lipodystrophy was first described in HIV-1-infected patients in 1998 [1–5]. The main clinical feature is subcutaneous fat loss or lipoatrophy of the face, limbs, and buttocks [6,7]. Patients can also experience fat accumulation within the abdomen, neck or breasts [8,9]. The pathogenesis of lipoatrophy appears to be multifactorial. Contributing factors are CD4þ lymphocyte cell count, HIV clinica...
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HIV-associated lipodystrophy syndrome affects approximately 50% of HIV-positive patients, particularly those receiving antiretroviral therapy based on nucleoside reverse transcriptase inhibitors and protease inhibitors. Growing evidence suggests that certain antiretroviral drugs may precipitate or exacerbate lipoatrophy and associated metabolic abnormalities, and this is an important considerat...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2012
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/cis745